Dehydrative allylation of P-H species under metal-free conditions

Xiaobo Yang,^a Bowen Li,^a Huicong Xing,^a Ju Qiu,^a Teck-Peng Loh,^ab and Peizhong Xie^a*

^a School of Chemistry and Molecular Engineering, Nanjing Tech University, Nanjing 211816, P. R. China.

b Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371.

Abstract: An environmentally benign protocol for C-P bond construction was developed under metal- and solvent-free conditions. In the presence of B(C₆F₅)₃, wide-spectrum P-H species, including dialkylphosphite, hypophosphite ester, and secondary phosphine oxides, can be successfully incorporated into the dehydrative cross-coupling process with allylic alcohols delivering the corresponding allylic organophosphorus compounds in high yields.

Green Chem. 2021, 23, 1633-1637.（影响因子：10.182）

论文链接：https://pubs.rsc.org/en/content/articlepdf/2021/gc/d1gc00191d